"what happens if you use alchohol 120% and mount one of those isos on the virtual drive and change the drive letter in epsxe to e: then run the cd, does it work? If it does then your plugins are working okay and theres something wrong with your drive and if it doesnt well more work for you."

No it doesn't work, so it must be my plug-ins. Well I suppose I should be comforted by the fact that my drive is working okay I better try getting some new plug-ins then, unless there's another way to fix it. Thanks for your help by the way skakidd.