If I recall correctly, you can mount the game image using Alcohol and then use Alcohol to convert the image into an actual ISO format, instead of mds+mdf, and it will also make the image into BIN+CUE (CDRWin) format, which is what I do with game images for PSX all the time, and the CRCs always come out exactly the same when converted as the original image format. ISOBuster can oftentimes corrupt the game image when converting from one file format to another, as this has happened to me when converting Panzer Dragoon Saga for Sega Saturn before.