there's a new version of the desmume for mac. it's up to 0.9.8, and works on mountain lion now. seems like it's about time to update it.
EDIT
this definitely needs to be done. i was having frame rate issues with the previous version, getting an average of 40 FPS instead of the more desirable 60. the newest version fixed that, i am now running at a full 60 FPS, the sounds is crisper, and visuals are better as well. it also adds a lot more options for changing settings, which is very nice as well.
here's the link if needed: http://desmume.org/2012/08/06/desmum...-lion-support/
the DL link is on that page.