DS emulator problems.

I want to emulate Up for the DS for my show.I got the game file from here https://www.emuparadise.me/Nintendo_...50197-download. Since I use a mac the recommended emulator to use was DeSmuME. I download the Up file and it instantly goes to the unarchiver by clicking it. I try to connect it to DeSmuME but it does not work. Can someone explain what I need to get or what I am doing wrong?

I don't know mac but as long as the game is unzipped can you not just start desmume and then choose to load the file and run it?

Does DeSmuME not use a bios image also?

Never mind, I have it sorted.