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https://dolphin-emu.org/download/

Try using the latest development build (after attempting the above), I don't notice any oddities with the Wiimote's functionality there

(also, minor quip [and...

Before I begin, I'm not surprised that 3.5 worked well on this while it did, as it's a much, much older version and didn't have to do things as accurately as the later versions/revisions do

Now,...

You could try extracting it elsewhere, like the desktop, and see if it still does the same thing

You could also try using LLE if you're using HLE.. Apparently it's one of the games that has issues...

1. which game/games is this present in?

2. which audio backend are you using (DSound, XAudio2, OpenAL)

2A. are you using LLE or HLE (if LLE, are you running it on a separate thread and have the...